ISU Students Win Research Creativity Award with 3D-printing Technology
Under the College of Medical Science and Technology, students from the Department of Medical Science and Biotechnology received research grants from the National Science and Technology Council (NSTC) for undergraduate projects in the 2023 academic year. Their study, “Deconstructing the Degrading Microbial Community of 3D Bioprinted Immobilized Particles on Plasticizer Treatment Using a Third-Generation Sequencing System,” demonstrated exceptional innovation in medical technology. In 2024, their outstanding research earned them the prestigious Research Creativity Award, distinguishing them among elite participants. This achievement underscores ISU’s strong foundation and cutting-edge potential in medical science and biotechnology.
As plastic waste accumulates, endocrine-disrupting plasticizers seep into soil and water systems, posing long-term ecological threats. The Research Creativity Award-winning project addresses this issue through low-temperature bioprinting technology. The research team has developed 3D-printed scaffolds that support plasticizer-degrading bacteria identified in their previous studies. These scaffolds create an optimal growth environment by supplying essential nutrients while shielding the bacteria from external microbial interference. This controlled setting enhances bacterial efficiency in breaking down plasticizers, offering a promising bioremediation solution.
Chien-Yu Liu, a senior in the Department of Medical Science and Biotechnology and recipient of the award, highlighted that the research integrates innovative low-temperature 3D bioprinting with advanced third-generation sequencing to analyze microbial changes before and after plasticizer degradation. The study employs abundance analysis, principal component analysis, clustering analysis, and phylogenetic classification to investigate interactions between degrading bacteria and environmental microorganisms, offering valuable insights for advancing plasticizer degradation technology. Liu expressed gratitude to ISU and her advisor, Dr. Chien-Sen Liao, for his guidance. She noted that presenting her research not only strengthened her professional expertise but also deepened her academic exploration, allowing her to contribute to scientific progress.
Dr. Liao, Chair of the Department of Medical Science and Biotechnology, emphasized that securing NSTC Research Grants for undergraduate students is already a remarkable achievement, and receiving this prestigious recognition further validates the dedication of both faculty and students. This success stems from motivation, perseverance, and accumulated experience, showcasing ISU students’ exceptional theoretical and practical expertise. As a comprehensive university, ISU fosters research talent across disciplines by supporting research projects, academic journal publications, and domestic and international patent applications. By aligning with Taiwan and the global talent market, ISU is a key hub for cultivating technological leaders committed to sustainable development worldwide.
